中央大学 小松研究室(生命分子化学)

研究業績

原著論文・総説

Nonbubble-Propelled Biodegradable Microtube Motors Consisting Only of Protein
N. Sugai, Y. Morita, T. Komatsu
Chem. Asian J. 2019, 14, 2953−2957. AbstractNEW
 ・Selected as a "Very Important Paper" (VIP)

Protein Microtube Motors with a Pt Nanoparticle Interior and Avidin Exterior for Self-Propelled Transportation, Separation, and Stirring
Y. Nakai, N. Sugai, H. Kusano, Y. Morita, T. Komatsu
ACS Appl. Nano Mater. 2019, 2, 4891−4899. AbstractNEW
 ・Cover Image

        

Hemoglobin(βC93A)-Albumin Cluster: Mutation of Cysteine-β93 to Alanine Allows Moderate Reduction of O2 Affinity by Inositol Hexaphosphate
Y. Morita, K. Igarashi, R. Funaki, T. Komatsu
ChemBioChem 2019, 20, 1684−1687. AbstractNEW

Further Evidence Regarding the Important Role of Chlorine Atoms of Aripiprazole on Binding to the Site II Area of Human Albumin
K. Sakurama, K. Nishi, S. Imoto, M. Hashimoto, T. Komatsu, Y. Morita, K. Taguchi, M. Otagiri, K. Yamasaki
J. Pharm. Sci. 2019, 108, 1890−1895. Abstract

酵素反応で自走するマイクロチューブモーター ―バイオメディカル領域での応用を目指して
小松晃之、菅井夏穂
月刊『化学』(化学同人), 2019, 74, 66−67. Content

Hemoglobin-Albumin Clusters Prepared using N-Succinimidyl 3-Maleimidopropionate as an Appropriate Crosslinker
R. Funaki, T. Kashima, W. Okamoto, S. Sakata, Y. Morita, M. Sakata, T. Komatsu
ACS Omega 2019, 4, 3228−3233. Abstract
 ・Open Access Article

Physicochemical Properties and Crystal Structures of Recombinant Canine and Feline Serum Albumins
T. Komatsu, K. Kihira, K. Yamada, K. Yokomaku, M. Akiyama, Y. Morita
Int. J. Microgravity Sci. Appl. 2019, 36, 360104:1−6. Abstract

Hemoglobin-Albumin Cluster: Physiological Responses after Exchange Transfusion into Rats and Blood Circulation Persistence in Dogs
H. Iwasaki, K. Yokomaku, M. Kureishi, K. Igarashi, R. Hashimoto, M. Kohno, M. Iwazaki, R. Haruki, M. Akiyama, K. Asai, Y. Nakamura, R. Funaki, Y. Morita, T. Komatsu
Art. Cells Nanomed. Biotechnol. 2018, 46, S621−S629. Abstract

Quaternary Structure Analysis of a Hemoglobin Core in Hemoglobin-Albumin Cluster
Y. Morita, T. Yamada, M. Kureishi, K. Kihira, T. Komatsu
J. Phys. Chem. B 2018, 122, 12031−12039. Abstract

Stratiform Protein Microtube Reactors Containing Glucose Oxidase Layer
R. Adachi, M. Akiyama, Y. Morita, T. Komatsu
Chem. Asian J. 2018, 13, 2796−2799. Abstract

Bulky Iodotriazolium Tetrafluoroborates as Highly Active Halogen-Bonding-Donor Catalysts
R. Haraguchi, S. Hoshino, M. Sakai, S. Tanazawa, Y. Morita, T. Komatsu, S. Fukuzawa
Chem. Commun. 2018, 54, 10320−10323. Abstract

Transparent Protein Microtubule Motors with Controllable Velocity and Biodegradability
N. Sugai, Y. Nakai, Y. Morita, T. Komatsu
ACS Appl. Nano Mater. 2018, 1, 3080−3085. Abstract
 ・Cover Image

        

A Novel Hemoglobin-Based Oxygen Carrier Bound with Albumin Shows Neuroprotection with Possible Antioxidant Effects
M. Gekka, T. Abumiya, T. Komatsu, R. Funaki, K. Kurisu, D. Shimbo, M. Kawabori, T. Osanai, N. Nakayama, K. Kazumata, K. Houkin
Stroke 2018, 49, 1960−1968. Abstract

Core-Shell Protein Clusters Comprising Haemoglobin and Recombinant Feline Serum Albumin as an Artificial O2 Carrier for Cats
K. Yokomaku, M. Akiyama, Y. Morita, K. Kihira, T. Komatsu
J. Mater. Chem. B 2018, 6, 2417−2425. Abstract
 ・Highlighted by Chemistry World
 ・Cover Image

        

Self-Propelled Soft Protein Microtubes with a Pt Nanoparticle Interior Surface
S. Kobayakawa, Y. Nakai, M. Akiyama, T. Komatsu
Chem. Eur. J. 2017, 23, 5044−5050. Abstract
 ・Highlighted by Chemistry World
 ・Cover Image  

        

Structural Insights into a Hemoglobin-Albumin Cluster in Aqueous Medium
R. Shinohara, T. Yamada, B. Schade, C. Böttcher, T. Sato, N. Sugimura, T. Shibue, T. Komatsu
J. Phys. Chem. Lett. 2017, 8, 819−824. Abstract
 ・Featured in Spotlights

Glycoprotein Nanotube Traps Influenza Virus
S. Yuge, M. Akiyama, M. Ishii, H. Namkoong, K. Yagi, Y. Nakai, R. Adachi, T. Komatsu
Chem. Lett. 2017, 46, 95−97. Abstract
 ・Selected as an "Editor's Choice"
 ・Open Access Article

Artificial Blood for Dogs
K. Yamada, K. Yokomaku, M. Kureishi, M. Akiyama, K. Kihira, T. Komatsu
Sci. Rep. 2016, 6, 36782:1−11. Abstract
 ・Open Access Article

Influence of Molecular Strcuture on O2-Binding Properties and Blood Circulation of Hemoglobin-Albumin Clusters
K. Yamada, K. Yokomaku, R. Haruki, K. Taguchi, S. Nagao, T. Maruyama, M. Otagiri, T. Komatsu
PLoS One 2016, 11, e149526:1-15. Abstract
 ・Open Access Article

Highly Sensitive Detection of Organophosphorus Pesticides using 5,10,15,20-Tetrakis(4-hydroxyphenyl)porphyrin
T. Murakami, Y. Iwamuro, S. Chinaka, N. Takayama, T. Komatsu
Anal. Sci. 2015, 31, 1325−1328. Abstract
 ・Open Access Article

Nanotube Reactor with a Lipase Wall Interior for Enzymatic Ring-Opening Oligomerization of Lactone
Y. Amano, T. Komatsu
Chem. Lett. 2015, 44, 1646−1648. Abstract

Safety Evaluation of Hemoglobin-Albumin Cluster "HemoAct" as a Red Blood Cell Substitute
R. Haruki, T. Kimura, H. Iwasaki, K. Yamada, I. Kamiyama, M. Kohno, K. Taguchi, S. Nagao, T. Maruyama, M. Otagiri, T. Komatsu
Sci. Rep. 2015, 5, 12778:1-9. Abstract
 ・Open Access Article

Core-Shell Clusters of Human Haemoglobin A and Human Serum Albumin: Artificial O2-Carriers Having Various O2-Affinities
T. Kimura, R. Shinohara, C. Böttcher, T. Komatsu
J. Mater. Chem. B 2015, 3, 6157−6164. Abstract
 ・Open Access Article
 ・Front Cover

        

Cross-Linked Human Serum Albumin Dimer has the Potential for Use as a Plasma-Retaining Agent for the Fatty Acid-Conjugated Antidiabetic Drugs
K. Taguchi, V. Chuang, K. Yamasaki, Y. Urata, R. Tanaka, M. Anraku, H. Seo, K. Kawai, T. Maruyama, T. Komatsu, M. Otagiri
J. Pharm. Pharmacol. 2015, 67, 255−263. Abstract

Hemoglobin-Albumin Cluster Incorporating a Pt Nanoparticle: Artificial O2 Carrier with Antioxidant Activities
H. Hosaka, R. Haruki, K. Yamada, C. Böttcher, T. Komatsu
PLoS One 2014, 9, e110541:1-9. Abstract
 ・Open Access Article

Haemoglobin Wrapped Covalently by Human Serum Albumin Mutants Containing Mn(III) Protoporphyrin IX: An O2 Complex Stable in H2O2 Solution
Y. Daijima, T. Komatsu
Chem. Commun. 2014, 50, 14716−14719. Abstract
 ・Open Access Article
 ・Front Cover

        

人工酸素運搬体(赤血球代替物)の開発 =せまりくる"血液不足"の危機を乗り越えるための切り札=
小松晃之
化学と工業, 2014, 67, 677−679. Contents

An Escherichia coli Trap in Human Serum Albumin Microtubes
S. Yuge, M. Akiyama, T. Komatsu
Chem. Commun. 2014, 50, 9640−9643. Abstract
 ・Open Access Article
 ・Highlighted by Chemistry World
 ・Front Cover

        

Fluorescence Dimer and Fiber of meso-Tetrakis{o-(isonicotinoylamino)phenyl}porphyrin Connected by Pd(II) Coordinations
S. Kasuya, Y. Yamazawa, N. Sugimura, T. Shibue, T. Komatsu
Chem. Lett. 2014, 43, 1008−1010. Abstract
 ・Open Access Article

Size-Dependent Dextran Loading in Protein Nanotube with an Interior Wall of Concanavalin A
Y. Shiraishi, M. Akiyama, T. Sato, M. Hattori, T. Komatsu
Polym. Adv. Technol. 2014, 25, 1247−1251. Abstract

Superoxide Dismutase Activity of the Naturally Occurring Human Serum Albumin-Copper Complex without Hydroxyl Radical Formation
R. Kato, M. Akiyama, H. Kawakami, T. Komatsu
Chem. Asian J. 2014, 8, 83−86. Abstract

Gold Nanoparticle Inclusion into Protein Nanotubes as a Layered Wall Component
S. Goto, Y. Amano, M. Akiyama, C. Böttcher, T. Komatsu
Langmuir 2013, 29, 14923−14930. Abstract

Human Serum Albumin Mutants Complexed Mn(III) Protoporphyrin IX as Superoxide Dismutase Mimics
R. Kato, Y. Kobayashi, M. Akiyama, T. Komatsu
Dalton Trans. 2013, 42, 15889−15892. Abstract

Covalent Core-Shell Architecture of Hemoglobin and Human Serum Albumin as an Artificial O2 Carrier
D. Tomita, T. Kimura, H. Hosaka, Y. Daijima, R. Haruki, K. Ludwig, C. Böttcher, T. Komatsu
Biomacromolecules 2013, 14, 1816−1825. Abstract

Structure and Photocatalytic Activity of Iron Oxide Nanotubes Prepared from Ferritin
R. Kato, T. Komatsu
J. Inorg. Organomet. Polym. 2013, 23, 167−171. Abstract

Human Serum Albumin-Based Peroxidase Having an Iron Protoporphyrin IX in Artificial Heme Pocket
K. Watanabe, N. Isihikawa, T. Komatsu
Chem. Asian J. 2012, 7, 2534−2537. Abstract

Protein-Based Nanotubes for Biomedical Applications (Feature Article)
T. Komatsu
Nanoscale 2012, 4, 1910−1918. Abstract
 ・Front Cover

        

Human Serum Albumin Nanotubes with Esterase Activity
T. Komatsu, T. Sato, C. Böttcher
Chem. Asian J. 2012, 7, 201−206. Abstract

Protein Nanotube Arrays Immobilized on Solid Substrates: Molecular Trap in Aqueous Medium
R. Kato, T. Komatsu
Chem. Lett. 2011, 40, 1338−1339. Abstract

Virus Trap in Human Serum Albumin Nanotube
T. Komatsu, X. Qu, H. Ihara, M. Fujihara, H. Azuma, H. Ikeda
J. Am. Chem. Soc. 2011, 133, 3246−3248. Abstract
 ・Highlighted by Chemistry World

Protein Nanotubes Bearing a Magnetite Surface Exterior
T. Komatsu, N. Kobayashi
Polym. Adv. Technol. (Prof. E. Tsuchida Special Issue) 2011, 22, 1315−1318. Abstract

Protein Nanotubes with an Enzyme Interior Surface
T. Komatsu, H. Terada, N. Kobayashi
Chem. Eur. J. 2011, 17, 1849−1854. Abstract

Superior Plasma Retension of a Cross-Linked Human Serum Albumin Dimer in Nephrotic Rats as a New Type of Plasma Expander
K. Taguchi, Y. Urata, M. Anraku, H. Watanabe, K. Kawai, T. Komatsu, E. Tsuchida, T. Maruyama, M. Otagiri
Drug Metab. Dispos. 2010, 38, 2124−2129. Abstract

Molecular Insight of Intrinsic Heme Distortion to the Ligand Binding in Hemoprotein
S. Neya, M. Suzuki, T. Hoshino, H. Ode, K. Imai, T. Komatsu, A. Ikezaki, M. Nakamura, Y. Furutani, H. Kandori
Biochemistry 2010, 49, 5642−5650. Abstract

Solid Nanotubes Comprising α-Fe2O3 Nanoparticles Prepared from Ferritin Protein
X. Qu, N. Kobayashi, T. Komatsu
ACS Nano 2010, 4, 1732−1738. Abstract

Molecular Capture in Protein Nanotubes
X. Qu, T. Komatsu
ACS Nano 2010, 4, 563−573. Abstract
 ・Highlighted by Nanowerk

The Role of an Amino Acid Triad at the Entrance of the Heme Pocket in Human Serum Albumin for O2 and CO Binding to Iron Protoporphyrin IX
T. Komatsu, A. Nakagawa, S. Curry, E. Tsuchida, K. Murata, N. Nakamura, H. Ohno
Org. Biomol. Chem. 2009, 7, 3836−3841. Abstract

Structural and Mutagenic Approach to Create Human Serum Albumin-Based Oxygen Carrier and Photosensitizer (Review Article)
T. Komatsu, A. Nakagawa, X. Qu
Drug Metab. Pharmacokinet. 2009, 24, 287−299. Abstract

O2 Binding Properties of Human Serum Albumin Quadruple Mutants Complexed Iron Protoporphyrin IX with Axial His-186 Coordination
A. Nakagawa, T. Komatsu, S. Curry, E. Tsuchida
Chem. Lett. 2009, 38, 776−777. Abstract

Artificial Oxygen Carriers, Hemoglobin Vesicles and Albumin-Hemes Based on Bioconjugate Chemistry (Review Article)
E. Tsuchida, K. Sou, A. Nakagawa, H. Sakai, T. Komatsu, K. Kobayashi
Bioconjugate Chem. 2009, 20, 1419−1440. Abstract
 ・Front Cover

        

Functional Evaluation of Iron Oxypyriporphyrin in Protein Heme Pocket
S. Neya, M. Suzuki, H. Ode, T. Hoshino, Y. Furutani, H. Kandori, H. Hori, K. Imai, T. Komatsu
Inorg. Chem. 2008, 47, 10771−10778. Abstract

Protein Nanotubes Comprised of an Alternate Layer-by-Layer Assembly using a Polycation as an Electrostatic Glue
X. Qu, G. Lu, E. Tsuchida, T. Komatsu
Chem. Eur. J. 2008, 14, 10303−10308. Abstract

Human Serum Albumin Nanotubes Comprising Layer-by-Layer Assembly with Polycation
G. Lu, E. Tsuchida, T. Komatsu
Chem. Lett. 2008, 37, 972−973. Abstract

Structure, Photophysical Property, and Cytotoxicity of Human Serum Albumin Complexed with Tris(dicarboxymethylene)[60]fullerene
X. Qu, T. Komatsu, T. Sato, O. Glatter, H. Horinouchi, K. Kobayashi, E. Tsuchida
Bioconjugate Chem. 2008, 19, 1556−1560. Abstract

Enhanced Radiation Response of a Solid Tumor with the Artificial Oxygen Carrier 'Albumin-Heme'
H. Horinouchi, H. Yamamoto, T. Komatsu, Y. Huang, E. Tsuchida, K. Kobayashi
Cancer Sci. 2008, 99, 1274−1278. Abstract

O2 Binding to Human Serum Albumin Incorporating Iron Porphyrin with a Covalently Linked Methyl-L-Histidine Isomer
A. Nakagawa, T. Komatsu, M. Iizuka, E. Tsuchida
Bioconjugate Chem. 2008, 19, 581−584. Abstract

Genetic Engineering of the Heme Pocket in Human Serum Albumin: Modulation of O2 Binding of Iron Protoporphyrin IX by Variation of Distal Amino Acids
T. Komatsu, A. Nakagawa, P. A. Zunszain, S. Curry, E. Tsuchida
J. Am. Chem. Soc. 2007, 129, 11286−11295. Abstract

O2-Binding Albumin Thin Films: Solid Membranes of Poly(ethylene glycol)-Conjugated Human Serum Albumin Incorporating Iron Porphyrin
A. Nakagawa, T. Komatsu, Y. Huang, G. Lu, E. Tsuchida
Bioconjugate Chem. 2007, 18, 1673−1677. Abstract

Artificial Hemoprotein Nanotubes
G. Lu, T. Komatsu, E. Tsuchida
Chem. Commun. 2007, 2980−2982. Abstract
 ・Highlighted by Chemical Science

Influence of O2-Carrying Plasma Hemoprotein "Albumin-Heme" on Complement System and Platelet Activation in vitro and Physiological Responses to Exchange Transfusion
T. Komatsu, Y. Huang, S. Wakamoto, H. Abe, M. Fujihara, H. Azuma, H. Ikeda, H. Yamamoto, H. Horinouchi, K. Kobayashi, E. Tsuchida
J. Biomed. Mater. Res. 2007, 81A, 821−826. Abstract

Induced Long-Range Attractive Potentials of Human Serum Albumin by Ligand Binding
T. Sato, T. Komatsu, A. Nakagawa, E. Tsuchida
Phys. Rev. Lett. 2007, 98, 208101-1−4. Abstract

meso-Tetrakis(α,α,α,α-o-amidophenyl)porphinatoiron(II) Bearing a Proximal Histidyl Group at the β-pyrrolic Position via an Acyl Bond: Synthesis and O2 Coordination in Aqueous Media
A. Nakagawa, T. Komatsu, E. Tsuchida
Chem. Lett. 2007, 36, 640−641. Abstract

Photosensitized Reduction of Water to Hydrogen using Human Serum Albumin Complexed with Zinc Protoporphyrin IX
T. Komatsu, R.-M. Wang, P. A. Zunszain, S. Curry, E. Tsuchida
J. Am. Chem. Soc. 2006, 128, 16297−16301. Abstract
 ・Highlighted by Chemistry World

PEGylated Albumin-Heme as an Oxygen-Carrying Plasma Expander: Exchange Transfusion into Acute Anemia Rat Model
Y. Huang, T. Komatsu, H. Yamamoto, H. Horinouchi, K. Kobayashi, E. Tsuchida
Biomaterials 2006, 27, 4477−4483. Abstract

Poly(ethylene glycol)-Conjugated Human Serum Albumin Including Iron Porphyrins: Surface Modification Improves the O2-Transporting Ability
Y. Huang, T. Komatsu, R.-M. Wang, A. Nakagawa, E. Tsuchida
Bioconjugate Chem. 2006, 17, 393−398. Abstract

Human Serum Albumin Hybrid Incorporating Tailed Porphyrinatoiron(II) in the α,α,α,β-Conformer as an O2-Binding Site
A. Nakagawa, T. Komatsu, M. Iizuka, E. Tsuchida
Bioconjugate Chem. 2006, 17, 146−151. Abstract

Albumin Clusters: Structurally Defined Protein Tetramer and Oxygen Carrier Including Thirty-Two Iron(II) Porphyrins
T. Komatsu, Y. Oguro, A. Nakagawa, E. Tsuchida
Biomacromolecules 2005, 6, 3397−3403. Abstract

O2 and CO Binding Properties of Artificial Hemoproteins Formed by Complexing Iron Protoporphyrin IX with Human Serum Albumin Mutants
T. Komatsu, N. Ohmichi, A. Nakagawa, P. A. Zunszain, S. Curry, E. Tsuchida
J. Am. Chem. Soc. 2005, 127, 15933−15942. Abstract
 ・Highlighted by Chemistry World

Heat-Resistant Oxygen-Carrying Hemoproteins Consist of Recombinant Xylanases and Synthetic Iron(II) Porphyrin
T. Komatsu, S. Ishihara, E. Tsuchida, H. Nishide, C. Inokuma, S. Nakamura
Biomacromolecules 2005, 6, 1489−1494. Abstract

Human Serum Albumin Bearing Covalently Attached Iron(II) Porphyrins as O2-Coodination Sites
R.-M. Wang, T. Komatsu, A. Nakagawa, E. Tsuchida
Bioconjugate Chem. 2005, 16, 23−26. Abstract

Exchange Transfusion with Synthetic Oxygen-Carrying Plasma Protein "Albumin-Heme" into an Acute Anemia Rat Model after Seventy-Percent Hemodilution
T. Komatsu, H. Yamamoto, Y. Huang, H. Horinouchi, K. Kobayashi, E. Tsuchida
J. Biomed. Mater. Res. 2004, 71A, 644−651. Abstract

Physicochemical Characterization of Cross-Linked Human Serum Albumin Dimer and Its Synthetic Heme Hybrid as an Oxygen Carrier
T. Komatsu, Y. Oguro, Y. Teramura, S. Takeoka, J. Okai, M. Anraku, M. Otagiri, E. Tsuchida
Biochim. Biophys. Acta 2004, 1675, 21−31. Abstract

Dioxygenation of Human Serum Albumin Having a Prosthetic Heme Group in a Tailor-Made Heme Pocket
T. Komatsu, N. Ohmichi, P. A. Zunszain, S. Curry, E. Tsuchida
J. Am. Chem. Soc. 2004, 126, 14304−14305. Abstract

Synthesis of Protoheme IX Derivatives with a Covalently Linked Proximal-Base and Their Human Serum Albumin Hybrids as Artificial Hemoprotein
A. Nakagawa, N. Ohmichi, T. Komatsu, E. Tsuchida
Org. Biomol. Chem. 2004, 2, 3108−3112. Abstract

Exchange Transfusion with Entirely Synthetic Red-Cell Substitute Albumin-Heme into Rats: Physiological Responses and Blood Biochemical Tests
Y. Huang, T. Komatsu, H. Yamamoto, H. Horinouchi, K. Kobayashi, E. Tsuchida
J. Biomed. Mater. Res. 2004, 71A, 63−69. Abstract

Molecular Energy and Electron Transfer Assemblies Made of Self-Organized Lipid-Porphyrin Bilayer Vesicles
T. Komatsu, M. Moritake, E. Tsuchida
Chem. Eur. J. 2003, 9, 4626−4633. Abstract

Crystal Structural Analysis of Human Serum Albumin Complexed with Hemin and Fatty Acid
P. A. Zunszain, J. Ghuman, T. Komatsu, E. Tsuchida, S. Curry
BMC Struct. Biol. 2003, 3, 6. Abstract

Synthetic Dioxygen-Carrying Hemoprotein. Human Serum Albumin Including Iron(II) Complex of Protoporphyrin IX with an Axially Coordinated Histidylglycyl-Propionate
A. Nakagawa, T. Komatsu, N. Ohmichi, E. Tsuchida
Chem. Lett. 2003, 32, 504−505. Abstract

Human Serum Albumin Incorporating Synthetic Heme: Red Blood Cell Substitute without Hypertension by Nitric Oxide Scavenging
E. Tsuchida, T. Komatsu, Y. Matsukawa, A. Nakagawa, H. Sakai, K. Kobayashi, M. Suematsu
J. Biomed. Mater. Res. 2003, 64A, 257−261. Abstract

Oxygenation of Hypoxic Region in Solid Tumor by Administration of Human Serum Albumin Incorporating Synthetic Hemes
K. Kobayashi, T. Komatsu, A. Iwamaru, Y. Matsukawa, M. Watanabe, H. Horinouchi, E. Tsuchida
J. Biomed. Mater. Res. 2003, 64A, 48−51. Abstract

Thermostable Synthetic Hemoproteins: Thermophilic Xylanases Hybridized with Dioxygen- Carrying meso-Tetrakis(o-pivalamidophenyl)porphinatoiron(II) Derivative
T. Komatsu, S. Ishihara, H. Nishide, E. Tsuchida, C. Morokuma, S. Nakamura
Chem. Lett. 2003, 32, 108−109. Abstract

meso-Tetrakis[o-(N-methyl)pyridinium]porphyrin Ensembles with Axially Coordinated Cyclodextrin-Penetrating Phenethylimidazole: Reversible Dioxygen-Binding in Aqueous DMF Solution
T. Komatsu, S. Hayakawa, E. Tsuchida, H. Nishide
Chem. Commun. 2003, 50−51. Abstract

2003年以前の論文・総説は省略=


著 書(分担執筆)

Hemoglobin-Albumin Clusters as a Red Blood Cell Substitute
T. Komatsu
Albumin in Medicine. Pathological and Clinical Applications, Ed. M. Otagiri, V. T. Giam Chuang, p. 165−178 (Chapter 9), Springer (Tokyo, 2016) Abstract

タンパク質ナノチューブの合成と応用展開
小松晃之, 秋山元英
超分子材料の設計と応用展開, 監修: 原田 明, p. 64−71, シーエムシー出版(大阪, 2014

Albumin-Heme Oxygen Carriers
T. Komatsu
Hemoglobin-Based Oxygen Carriers as Red Cell Substitutes and Oxygen Therapeutics, Ed. H. W. Kim, A. G. Greenburg, p. 339−348 (Chapter 18), Springer-Verlag (Berlin Heidelberg, 2013) Abstract

Albumin-Heme as an O2-Carrying Plasma Protein
T. Komatsu
Human Serum Albumin −New Insights on its Structural Dynamics, Functional Impacts and Pharmaceutical Applications, Ed. M. Otagiri, p. 332−345 (Chapter 17), Sojo Univ. Pub. (Kumamoto, 2013)

交互積層法による蛋白質ナノチューブの合成
小松晃之
有機・無機・金属ナノチューブ-非カーボンナノチューブ系の最新技術と応用展開, 清水敏美, 木島 剛 編, p. 82−88, フロンティア出版(東京, 2008

Albumin-Heme: A Synthetic Heme-Based Oxygen Carrier
T. Komatsu, Y. Huang, H. Yamamoto, H. Horinouchi, K. Kobayashi, E. Tsuchida
Blood Substitutes, Ed. R. Winslow, p. 532−539 (Chapter 46), Elsevier (London, 2006)

Oxygen-Carrying Plasma Hemoprotein Including Synthetic Heme
T. Komatsu, E. Tsuchida
Artificial Oxygen Carrier. Its Front Line, Eds. K. Kobayashi, E. Tsuchida, H. Horinouchi, p. 193−204, Springer-Verlag (Tokyo, 2005)

Safety and Efficacy of Hemoglobin-Vesicles and Albumin-Hemes
K. Kobayashi, H. Horinouchi, M. Watanabe, Y. Izumi, Y. Teramura, A. Nakagawa, Y. Huang, K. Sou, H. Sakai, T. Komatsu, S. Takeoka, E. Tsuchida
Artificial Oxygen Carrier. Its Front Line, Eds. K. Kobayashi, E. Tsuchida, H. Horinouchi, p. 1−21, Springer-Verlag (Tokyo, 2005)

疎水ポルフィリン組織体の構築と酸素の運搬
西出宏之, 小松晃之, 土田英俊
ソフトマテリアルの新展開, 監修: 西 敏夫, p. 16−26, シーエムシー出版(東京, 2004

2003年以前の著書は省略=